Small animal - April 2021
Truth and dare: Are brachycephalic dogs really less healthy than other dogs?
The back story
There is increasing veterinary concern for the health and welfare of brachycephalic dogs.1-3 A backdrop of increasing evidence on health compromises associated with their exaggerated body morphology4-6 is exacerbated by recent marked rises in the popularity of certain brachycephalic breeds such as French Bulldogs, Pugs and English Bulldogs.7 Disorder predispositions associated with brachycephaly include respiratory disease,8,9 corneal ulceration,10,11 dystocia,12,13 spinal disease,14 and heat stroke and pneumonia15 in addition to shortened lifespans (8.6 years vs 12.7 years for non-brachycephalic dogs16). Some veterinarians now consider the issues of several popular brachycephalic breeds too compromised to even justify continued breeding.17 In the UK, the problems related to brachycephaly in dogs are so important that a national group called the Brachycephalic Working Group (BWG) has been established to try to gain a deeper understanding of these complex issues and to identify some routes forward.18
But what is the truth here about the health of brachycephalic dog? And how can veterinary professionals and veterinary practices contribute to mitigating the welfare harms that are associated with brachycephaly in dogs? To answer the first of these questions, anonymised veterinary clinical data from the VetCompass Programme19 were analysed to compare the probability of occurrence of common disorders between brachycephalic and non-brachycephalic dogs. Based on these results, a summary view of the relative health impact on dogs from brachycephaly could be inferred. This information could then be used as an evidence base to decide on the merits of taking actions to mitigate these harms.
The study plan
VetCompass collects anonymised clinical data from around 30% of primary-care veterinary practices in the UK.19 The study used a cohort design to identify all disorders recorded in a random sample of dogs under primary veterinary care during 2016. The breeds of the study dogs were categorised into four groups based on their typical skull-shape conformation20: brachycephalic, mesocephalic, dolichocephalic and crossbred dog types. Mesocephalic, dolichocephalic and crossbred dog types were further grouped as non-brachycephalic types for risk analyses. Additional information extracted on each dog included neuter and insurance status; absolute adult bodyweight (the mean of all bodyweight [kg] values recorded after 18 months old), age (at December 31, 2016); and relative adult bodyweight (either above or below the relevant breed-sex mean). A combined list of the 30 most common disorders among each of the brachycephalic and non-brachycephalic dog groups was generated. Multivariable statistical methods were used to account for confounding, given the prior evidence that brachycephalic and non-brachycephalic dogs differ widely in general characteristics such as bodyweight, age and neuter status.21,22 The study also compared these characteristics and reported the one-year period prevalence values for the 30 most common disorders of brachycephalic, and non-brachycephalic dogs. Risk-factor analyses applied random effects multivariable binary logistic regression modelling to evaluate associations between each of the common disorders and the brachycephalic/non-brachycephalic factor along with a fixed set of covariables included to account for confounding (absolute adult bodyweight, relative adult bodyweight, age, sex, neuter and insurance). Multivariable Poisson regression modelling was used to evaluate associations between the skulls shape and the count of disorders recorded during 2016.
Brachycephaly is common in dogs
The study included a random sample of 22,333 dogs attending 784 veterinary clinics. The breakdown by skull shape was 18.7% brachycephalic, 46.5% mesocephalic, 7.8% dolichocephalic and 26.94% crossbred. At a more summarised level, the population included 18.7% brachycephalic and 81.3% non-brachycephalic dogs.
Brachycephalic breeds are just different
Brachycephalic dogs (median age 3.31 years) were younger than mesocephalic (5.33 years; P <0.001), dolichocephalic (5.07 years; P <0.001) and crossbred dogs (3.74 years; P <0.001). Brachycephalic dogs (median adult bodyweight 8.75kg) were lighter than mesocephalic (16.98kg; P <0.001), dolichocephalic (25.80kg; P <0.001) and crossbred dogs (13.80kg; P < 0.001). Brachycephalic dogs (neutered 36.70%) were less likely to be neutered than mesocephalic (46.13%; P <0.001), dolichocephalic types (46.43%; P <0.001) and crossbred dogs (49.95%;P <0.001). Brachycephalic dogs (insured 11.47%) were less likely to be insured than mesocephalic (14.18%; P <0.001) or dolichocephalic dogs (16.06%; P <0.001) but insurance did not differ to crossbreds (12.55%; P = 0.101).
There are fewer brachycephalic breeds (34) than for the mesocephalic group (169) or dolichocephalic group (66). The most common brachycephalic breeds were not the ones typically promoted in the media: Chihuahua (22.91%), Shih-tzu (19.07%) and Cavalier King Charles Spaniel (10.43%). Within each skull shape group, the 15 most common breeds comprised a greater proportion of the brachycephalic dog types (98.37%) than mesocephalic types (83.69%; P <0.001) or dolichocephalic types 82.11%; P <0.001).
Brachycephalic breeds seem less healthy
Demographic differences between the skull shape groups means that direct comparison between the groups (i.e. univariable analysis) is likely to give misleading results. For example, if younger dogs are generally healthier than older dogs, then brachycephalic dogs will appear artifactually healthier because they are younger on average than other groups. To account for these effects, the study used multivariable analytic methods that took account of the differing age, bodyweight, neutering and insurance between the groups.
Across all dogs in the study, 65.84% had at least one disorder recorded during 2016. Multivariable logistic regression modelling showed that brachycephalic dogs had 1.27 times the odds of having at least one disorder diagnosed (95% CI 1.13-1.43; P <0.001) compared with crossbred types and was similarly predisposed compared with mesocephalic and dolichocephalic dogs. The median count of disorders diagnosed in each dog in the overall study during 2016 was 1 (IQR 0-2, range 0-17). Multivariable Poisson regression modelling showed that the brachycephalic dogs had a significantly higher count of disorders annually than mesocephalic, dolichocephalic and crossbred dogs.
The most common disorders diagnosed in the brachycephalic dogs were periodontal disease (prevalence = 11.63%), otitis externa (7.27%), obesity (6.38%) and anal sac impaction (5.97%). Following multivariable logistic regression analysis, the odds of 10 of the 30 common disorders (33.33%) differed between brachycephalic and non-brachycephalic types. Brachycephalic dogs had higher odds in 8/10 disorders: corneal ulceration (odds ratio 8.40); heart murmur (OR 3.52); umbilical hernia (OR 3.16); pododermatitis (OR 1.66); skin cyst (OR 1.52); patellar luxation (OR 1.40); otitis externa (OR 1.29); and anal sac impaction (OR 1.24). Brachycephalic dogs had lower odds in 2/10 disorders: undesirable behaviour (OR 0.52,) and claw injury (OR 0.45).
This study is the first large-scale direct comparison of the health of brachycephalic versus non-brachycephalic dogs using veterinary clinical records. The results provide strong evidence to support the position that brachycephalic dogs have reduced health overall compared with non-brachycephalic dogs. Brachycephalic dogs had higher odds of having at least one disorder and higher predicted annual disorder counts. Among the 30 most common disorders, brachycephalic types showed predispositions for 8/30 disorders compared with protections for just 2/30 disorders. These results take account of the differing demographic characteristics between the groups of dogs and therefore provide a more reliable evidence base on comparative health than many of the earlier univariable studies.
Recent rising popularity and ownership of Pugs,23 French Bulldogs21 and English Bulldogs24 have triggered growing concerns about brachycephalic health issues in dogs.18-25 However, the distribution of breeds in the current study show that there are many other common brachycephalic breeds that warrant concern, adding further complexity to the brachycephalic issue. It is also clear that the specific issues related to brachycephalism vary in their relative impacts across these breeds. But the overall message is clear; there are important implications from brachycephalism for the health of brachycephalic breeds.
If we now accept the truth that the health of brachycephalic dog breeds really is poorer overall than for non-brachycephalic dogs, the next question is what you dare to do about this? Your actions could be at a personal level as a veterinary professional, or at a practice level, or at a national level, eg. within Veterinary Ireland. To date, many individual veterinary professionals, practices and organisations have undertaken unilateral actions aimed at redressing the brachycephalic issue but the complexity of the brachycephalic problem has meant that many of these actions have had limited success to date. Indeed, many unilateral actions may even have led to overall harms. There is now an acceptance that the best actions on brachycephalism need to be collaborative and widely supported in order to have the greatest chance of meaningful success. To this end, the BWG18 was established in the UK in 2016 as a broad coalition of major stakeholders including breed clubs, animal charities, academia, government and veterinary organisations. The BWG aims to develop deeper understanding of the brachycephalic issues by sharing knowledge and to design effective actions by pooling resources. The group has published a series of position statements that may offer opportunities for you to implement in your own actions, those of your practice and in your wider veterinary organisational roles.26
1. Obesity has serious health implications for dogs in general, but especially for brachycephalic dogs.27 The BWG offers several specific calls to action for veterinary professionals to mitigate the negative impact from obesity on brachycephalic dogs.
2. Unnecessary and inappropriate use of images of brachycephalic dogs in public messaging perpetuates the appeal, and encourages impulsive ownership, of brachycephalic breeds. Your practice could dare to adopt a formal policy of avoiding inappropriate use of brachycephalic imagery in all practice-related public media.
3. BWG has developed a public-facing strapline of ‘Stop and think before buying a flat-faced dog’. There are substantial welfare harms from low-welfare breeding and high levels of relinquishment that result from the extreme popularity of some of these breeds. The strapline is designed to support these breeds and be used as a universal call to action to the public from any welfare-minded organisation. Your veterinary practice might dare to support your current clients by adopting this welfare-friendly message.
4. The full peer-reviewed paper behind this article has been summarised as a colourful infographic that supports the aims of the BWG (see Figure 1). You could dare to share this infographic with your clients on your social media.28
Let’s face it…
There is now overwhelming evidence on the negative health implications of brachycephaly on dogs and on the additional harms that sudden popularity has wrought on these breeds. As veterinary professionals, we are oath-bound to ‘promote the welfare of animals entrusted to my care’. This is the truth. It is time for action by those who dare.
Figure 1: VetCompass brachycephalic infographic.
Table 1: Relative odds of the 30 most common disorders in brachycephalic (n = 4,169) compared with non-brachycephalic (n = 18,079) dogs.
This article is a summary of a fuller report: ‘O’Neill DG, Pegram C, Crocker P, Brodbelt DC, Church DB, Packer RMA. Unravelling the health status of brachycephalic dogs in the UK using multivariable analysis. Scientific Reports. 2020;10(1):17251’ that is freely available Open Access at https://www.nature.com/articles/s41598-020-73088-y
Waters A. Brachycephalic tipping point: time to push the button? Veterinary Record. 2017;180(12):288.
BBC. Pedigree Dogs Exposed 2008 [Available from: http://www.bbc.co.uk/pressoffice/pressreleases/stories/2008/08_august/19/dogs.shtml.
Limb M. Dutch crackdown on brachycephalic breeds. Vet Rec. 2019;184:693.
FVE, FECAVA. Breeding healthy dogs: The effect of selective breeding on the health and welfare of dogs: FVE & FECAVA; 2018 [Available from: https://www.fecava.org/wp-content/uploads/2019/03/2018_06_Extreme_breeding_adopted.pdf
FECAVA, FVE. Breeding For Extreme Conformations: What Is The Problem? : FECAVA & FVE; 2018 [Available from: https://www.fecava.org/wp-content/uploads/2019/03/FLYER_Extreme-breeding_RVau21_06_18_BAT.pdf.
Gough A, Thomas A, O'Neill D. Breed Predispositions to Disease in Dogs and Cats. 3rd ed. Chichester, West Sussex: Wiley-Blackwell; 2018. 398 p.
The Kennel Club. Breed registration statistics: The Kennel Club Limited; 2020 [Available from: https://www.thekennelclub.org.uk/media-centre/breed-registration-statistics/.
O'Neill DG, Jackson C, Guy JH, Church DB et al. Epidemiological associations between brachycephaly and upper respiratory tract disorders in dogs attending veterinary practices in England. Canine Genetics and Epidemiology. 2015;2(1):10.
Packer RMA, Hendricks A, Tivers MS, Burn CC. Impact of facial conformation on canine health: Brachycephalic Obstructive Airway Syndrome. PLoS ONE. 2015;10(10):e0137496.
Packer RMA, Hendricks A, Burn CC. Impact of facial conformation on canine health: Corneal ulceration. PLoS ONE. 2015;10(5):1-16.
O'Neill D, Lee MM, Brodbelt DC, Church DB, Sanchez RF. Corneal ulcerative disease in dogs under primary veterinary care in England: epidemiology and clinical management. Canine Genetics and Epidemiology. 2017;4(1):5.
O'Neill DG, O'Sullivan AM, Manson EA, Church DB, et al. Canine dystocia in 50 UK first-opinion emergency-care veterinary practices: prevalence and risk factors. Veterinary Record. 2017;181(4).
O'Neill DG, O’Sullivan AM, Manson EA, Church DB, et al. Canine dystocia in 50 UK first-opinion emergency care veterinary practices: clinical management and outcomes. Veterinary Record. 2019;184:409.
Ryan R, Gutierrez-Quintana R, ter Haar G, De Decker S. Prevalence of thoracic vertebral malformations in French Bulldogs, Pugs and English Bulldogs with and without associated neurological deficits. The Veterinary Journal. 2017;221:25-9.
Feng T, McConnell C, O’Hara K, Chai J, Spadafori G. Nationwide Brachycephalic Breed Disease Prevalence Study. http://nationwidedvm.com/wp-content/uploads/2017/03/NWBrachycelphalicStudy0317.pdf; 2017.
O'Neill DG, Church DB, McGreevy PD, Thomson PC, Brodbelt DC. Longevity and mortality of owned dogs in England. The Veterinary Journal. 2013;198(3):638-43.
Farrow T, Keown AJ, Farnworth MJ. An exploration of attitudes towards pedigree dogs and their disorders as expressed by a sample of companion animal veterinarians in New Zealand. New Zealand Veterinary Journal. 2014;62(5):267-73.
BWG. The Brachycephalic Working Group: The Brachycephalic Working Group; 2021 [Available from: http://www.ukbwg.org.uk/.
VetCompass. VetCompass Programme London: RVC Electronic Media Unit; 2021 [Available from: http://www.rvc.ac.uk/VetCOMPASS/.
The Kennel Club. Breed Information Centre: The Kennel Club Limited; 2020 [Available from: https://www.thekennelclub.org.uk/search/breeds-a-to-z.
O'Neill DG, Baral L, Church DB, Brodbelt DC, Packer RMA. Demography and disorders of the French Bulldog population under primary veterinary care in the UK in 2013. Canine Genetics and Epidemiology. 2018;5(1):3.
O'Neill D, Coulson NR, Church DB, Brodbelt DC. Demography and disorders of German Shepherd Dogs under primary veterinary care in the UK. Canine Genetics and Epidemiology. 2017;4(1):7.
O'Neill DG, Darwent EC, Church DB, Brodbelt DC. Demography and health of Pugs under primary veterinary care in England. Canine Genetics and Epidemiology. 2016;3(1):1-12.
O'Neill DG, Skipper AM, Kadhim J, Church DB, Brodbelt DC, Packer RMA. Disorders of Bulldogs under primary veterinary care in the UK in 2013. PLOS ONE. 2019;14(6):e0217928.
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BWG. Vetcompass Infographics: UK Brachycephalic Working group; 2021 [Available from: http://www.ukbwg.org.uk/?page_id=490.
1) Which of the following disorders are associated with brachycephaly in dogs?
A. Heat stroke
b. Corneal ulceration
c. Parvovirus enteritis
2) What proportion of UK veterinary practices are currently sharing anonymised data with VetCompass?
3) What proportion of dogs overall are brachycephalic?
4) What was the most common disorder recorded in brachycephalic dogs?
A. Otitis externa
d. Corneal ulceration
E. Periodontal disease
5) How many of the 30 most common disorders were predisposed in brachycephalic dogs?
Answers: 1 A,B,D; 2E; 3C; 4E; 5D.